Some foods may help delay aging

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– Some foods may help delay aging.

GRANADA, Spain April 24 (UPI) — A substance found in foods like onions, cherries and bananas, as well as cereals, spices and red wine, may be key to delaying aging, says a Spanish study.
Researchers at the University of Granadas Institute of Biotechnology as well as researchers in Seville, Oviedo, Saragossa, Barcelona and Reus have concluded that the consumption of melatonin — a natural substance produced in small amounts by human beings and present in many types of food delays the oxidative damage and inflammatory processes typical of the old age.

Melatonin is found in foods including onions, cherries, bananas, corn, oats, rice, mint, lemon verbena, sage, thyme and red wine, according to the findings published in Free Radical Research, Experimental Gerontology, Journal of Pineal Research and Frontiers in Bioscience.

The researchers administered small amounts of melatonin to mice and observed that not only did this substance neutralize the oxidative stress and the inflammatory process caused by aging, but it also delayed its effects and increased longevity.

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Corn, oats, cherries and red wine’s high melatonin content can help delay ageing

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– Corn, oats, cherries and red wine’s high melatonin content can help delay ageing.

– A study carried out by researchers from the University of Granada’s Institute of Biotechnology proves that consuming melatonin neutralizes oxidative damage and delays the neurodegenerative process of ageing.

– In this study researchers used normal and genetically-modified mice which were subjected to accelerated cell ageing, although their results can also be applied to humans.

C@MPUS DIGITAL The Spanish Ageing Research Network (Red Nacional de Investigación del Envejecimiento), funded by Carlos III Health Institute and headed by professor Darío Acuña Castroviejo, from the University of Granada (Universidad de Granada), is very near to achieving one of today’s Science greatest goals: allowing humans to age in the best possible health conditions.

As well as from the UGR, researchers from the Spanish universities of Seville, Oviedo, Saragossa, Barcelona and Reus also took part in this study, concluding that the consumption of melatonin – a natural substance produced in small amounts by human beings and present in many types of food – delays the oxidative damage and inflammatory processes typical of the old age. Melatonin can be found in small amounts in some fruits and vegetables, like onions, cherries and bananas, and in cereals like corn, oats and rice, as well as in some aromatic plants, such as mint, lemon verbena, sage or thyme, and in red wine.

UGR participation in this study was leaded by professor Darío Acuña Castroviejo, member of the Institute of Biotechnology and lecturer at this University’s department of Physiology. Professor Acuña Castroviejo also coordinates the Spanish Ageing Research Network. Both normal and genetically-modified mice, with an accelerated cell ageing, were analysed. We proved, says professor Acuña Castroviejo, “that the first signs of ageing in animal tissues start at the age of five months [in mice] – equivalent to 30 human years of age – due to an increase in free radicals (oxygen and nitrogen), which cause an inflammatory reaction.”

The UGR researcher points out that such oxidative stress also has effects in animals’ blood, as blood cells have been proven to be “more fragile with the years and, therefore, their cell membranes become easier to break.

Use in mice

The authors of this innovative finding administered small amounts of melatonin to mice and observed that not only did this substance neutralize the oxidative stress and the inflammatory process caused by ageing, but it also delayed its effects, thus increasing longevity. In particular, the University of Granada’s goal was to analyse the mitochondrial function in mice and check their mitochondrial capacity to produce ATP – adenosine triphosphate – a molecule whose mission is to store the energy every cell needs to carry out its functions.

Professor Acuña Castroviejo highlights that chronic administration of melatonin in animals from the moment they stop producing this substance – five months of age in mice – helps counteract all age-related processes. Therefore, daily melatonin intake in humans from the age of 30 or 40 could prevent – or, at least, delay – illnesses related to ageing, free radicals and inflammatory processes, such as many neurodegenerative disorders (e.g. Parkinsons disease) and complications linked to other illnesses, like diabetes.

The researcher is confident that the Spanish Ministry of Health will soon legalise the use of melatonin since, being a substance naturally produced by the body, it cannot be patented and the drug industry would not make much profit out of its artificial production. However, “while the substance becomes legalised, humans should try to increase melatonin consumption through food, recommends professor Acuña Castroviejo.

The results of this study have been published in some of the world’s most prestigious medical journals, such as Free Radical Research, Experimental Gerontology, Journal of Pineal Research and Frontiers in Bioscience.-Universidad de Granada

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Red Wine, Corn, Oats, Cherries can help Delay Ageing

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– Red Wine, Corn, Oats, Cherries can help Delay Ageing

A study carried out by researchers from the University of Granada’s Institute of Biotechnology proves that consuming melatonin neutralizes oxidative damage and delays the neurodegenerative process of ageing. In this study researchers used normal and genetically-modified mice which were subjected to accelerated cell ageing, although their results can also be applied to humans.

The Spanish Ageing Research Network (Red Nacional de Investigación del Envejecimiento), funded by Carlos III Health Institute and headed by professor Darío Acuña Castroviejo, from the University of Granada (Universidad de Granada), is very near to achieving one of today’s Science greatest goals: allowing humans to age in the best possible health conditions.

As well as from the UGR, researchers from the Spanish universities of Seville, Oviedo, Saragossa, Barcelona and Reus also took part in this study, concluding that the consumption of melatonin – a natural substance produced in small amounts by human beings and present in many types of food – delays the oxidative damage and inflammatory processes typical of the old age. Melatonin can be found in small amounts in some fruits and vegetables, like onions, cherries and bananas, and in cereals like corn, oats and rice, as well as in some aromatic plants, such as mint, lemon verbena, sage or thyme, and in red wine.

UGR participation in this study was leaded by professor Darío Acuña Castroviejo, member of the Institute of Biotechnology and lecturer at this University’s department of Physiology. Professor Acuña Castroviejo also coordinates the Spanish Ageing Research Network. Both normal and genetically-modified mice, with an accelerated cell ageing, were analysed. We proved, says professor Acuña Castroviejo, “that the first signs of ageing in animal tissues start at the age of five months [in mice] – equivalent to 30 human years of age – due to an increase in free radicals (oxygen and nitrogen), which cause an inflammatory reaction.”

The UGR researcher points out that such oxidative stress also has effects in animals’ blood, as blood cells have been proven to be “more fragile with the years and, therefore, their cell membranes become easier to break.

Use in mice

The authors of this innovative finding administered small amounts of melatonin to mice and observed that not only did this substance neutralize the oxidative stress and the inflammatory process caused by ageing, but it also delayed its effects, thus increasing longevity. In particular, the University of Granada’s goal was to analyse the mitochondrial function in mice and check their mitochondrial capacity to produce ATP – adenosine triphosphate – a molecule whose mission is to store the energy every cell needs to carry out its functions.

Professor Acuña Castroviejo highlights that chronic administration of melatonin in animals from the moment they stop producing this substance – five months of age in mice – helps counteract all age-related processes. Therefore, daily melatonin intake in humans from the age of 30 or 40 could prevent – or, at least, delay – illnesses related to ageing, free radicals and inflammatory processes, such as many neurodegenerative disorders (e.g. Parkinsons disease) and complications linked to other illnesses, like diabetes.

The researcher is confident that the Spanish Ministry of Health will soon legalise the use of melatonin since, being a substance naturally produced by the body, it cannot be patented and the drug industry would not make much profit out of its artificial production. However, “while the substance becomes legalised, humans should try to increase melatonin consumption through food, recommends professor Acuña Castroviejo.

The results of this study have been published in some of the world’s most prestigious medical journals, such as Free Radical Research, Experimental Gerontology, Journal of Pineal Research and Frontiers in Bioscience
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High Melatonin Content Can Help Delay Aging, Mouse Study Suggests

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– High Melatonin Content Can Help Delay Aging, Mouse Study Suggests.

A study carried out by researchers from the University of Granada’s Institute of Biotechnology shows that consuming melatonin neutralizes oxidative damage and delays the neurodegenerative process of aging. In this study researchers used normal and genetically-modified mice which were subjected to accelerated cell aging. Researchers believe their results can also be applied to humans.

The Spanish aging Research Network (Red Nacional de Investigación del Envejecimiento), funded by Carlos III Health Institute and headed by professor Darío Acuña Castroviejo, from the University of Granada (Universidad de Granada), is very near to achieving one of sciences greatest goals: allowing humans to age in the best possible health conditions.

As well as from the UGR, researchers from the Spanish universities of Seville, Oviedo, Saragossa, Barcelona and Reus also took part in this study, concluding that the consumption of melatonin – a natural substance produced in small amounts by human beings and present in many types of food – delays the oxidative damage and inflammatory processes typical of the old age. Melatonin can be found in small amounts in some fruits and vegetables, like onions, cherries and bananas, and in cereals like corn, oats and rice, as well as in some aromatic plants, such as mint, lemon verbena, sage or thyme, and in red wine.

UGR participation in this study was leaded by professor Darío Acuña Castroviejo, member of the Institute of Biotechnology and lecturer at this University’s department of Physiology. Professor Acuña Castroviejo also coordinates the Spanish aging Research Network. Both normal and genetically-modified mice, with an accelerated cell aging, were analysed. We proved, says professor Acuña Castroviejo, “that the first signs of aging in animal tissues start at the age of five months [in mice] – equivalent to 30 human years of age – due to an increase in free radicals (oxygen and nitrogen), which cause an inflammatory reaction.”

The UGR researcher points out that such oxidative stress also has effects in animals’ blood, as blood cells have been proven to be “more fragile with the years and, therefore, their cell membranes become easier to break.

Use in mice

The authors administered small amounts of melatonin to mice and observed that not only did this substance neutralize the oxidative stress and the inflammatory process caused by aging, but it also delayed its effects, thus increasing longevity. In particular, the University of Granada’s goal was to analyse the mitochondrial function in mice and check their mitochondrial capacity to produce ATP – adenosine triphosphate – a molecule whose mission is to store the energy every cell needs to carry out its functions.

Professor Acuña Castroviejo highlights that chronic administration of melatonin in animals from the moment they stop producing this substance – five months of age in mice – helps counteract all age-related processes. Therefore, the researcher asserts, daily melatonin intake in humans from the age of 30 or 40 could prevent – or, at least, delay – illnesses related to aging, free radicals and inflammatory processes, such as many neurodegenerative disorders (e.g. Parkinsons disease) and complications linked to other illnesses, like diabetes.

The researcher is confident that the Spanish Ministry of Health will soon legalise the use of melatonin since, being a substance naturally produced by the body, it cannot be patented and the drug industry would not make much profit out of its artificial production. However, “while the substance becomes legalised, humans should try to increase melatonin consumption through food, recommends professor Acuña Castroviejo.

The results of this study have been published in several medical journals, including Free Radical Research, Experimental Gerontology, Journal of Pineal Research and Frontiers in Bioscience.

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Anti-Ageing Foods Revealed

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– Anti-Ageing Foods Revealed.

A new study has found that consuming melatonin – a natural substance produced in small amounts by humans and present in certain types of food – delays the oxidative damage and inflammatory processes typical of old age.

Alec Holden, it seems, really is onto something. The retired engineer who today celebrated his 100th birthday (winning £25 000 on a wager that he would make it to his century) claims that the key to his longevity was a daily diet of porridge.

And anti-ageing melatonin can be found in small amounts in some fruits and vegetables, like onions, cherries and bananas, and in cereals like corn, porridge oats and rice, as well as in some aromatic plants including mint, lemon verbena, sage and thyme, and in red wine.

Head researcher of the study, physiologist Darío Acuña Castroviejo, says that the first signs of ageing are caused by an increase in free radicals (oxygen and nitrogen), which cause an inflammatory reaction – something that melatonin prevents.

In fact, consuming just small amounts of melatonin not only neutralises the oxidative stress and the inflammatory process caused by ageing, but also delayed its effects, thus increasing longevity, according to researchers from the University of Granada’s Institute of Biotechnology.

The team believe that a daily dose of melatonin from the age of 30 or 40 could prevent – or, at least, delay – illnesses related to ageing, free radicals and inflammatory processes, such as many neurodegenerative disorders like Parkinsons disease and complications linked to other illnesses, like diabetes.

Being a substance naturally produced by the body, melatonin cannot be patented and the drug industry would not make much profit out of its artificial production. However, Acuña Castroviejo recommends that people should try to increase melatonin consumption through the food they eat.

The results of this study have been published in some of the world’s most prestigious medical journals, such as Free Radical Research, Experimental Gerontology, Journal of Pineal Research and Frontiers in Bioscience.

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