A study demonstrates that ibuprofen improves bone repair after surgery or a fracture

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A study conducted at the University of Granada hasdemonstrated that ibuprofen ­–a non-steroidal anti-inflammatory drug (NSAID)­– has beneficial effects on bone repair after afracture or following bone surgery.

In vitro tests demonstrated that –unlike other NSAIDs– when a therapeutic dose of ibuprofen is administered, it has no negative effects on the proliferation and synthesis of obsteoblast osteocalcin, a cell which is directly involved in the formation and regeneration of bones.

Osteoblast cells are bone cells that synthesize the bone matrix. Consequently, osteoblasts play a major role in bone development, growth, maintenance and repair.

Positive Results

In an article recently published in the prestigious Journal of Bone and Mineral Metabolism, the University of Granada researchers report the positive effects of ibuprofen on bone repair. The researchers are members of the research group BIO277, which studies the effects of different pharmacological and non-pharmacological therapies on obsteoblast cells.

The primary author of this article, Concepción Ruiz Rodríguez, a professor at the University of Granada Nursing Department states that «up to date, we had little information on the effects of ibuprofen on osteoblast cells». The University of Granada study demonstrates that a therapeutic dose of ibuprofen (5-25µm.) does not inhibit the proliferation and synthesis of osteocalcinin the MG-63 cell line. However, when higher doses are administered (>25 µm.) they may activate other cells, which might explain theexpression of membrane markers and the decrease in the phagocytic capacity.

Source: University of Granada

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Researchers develop an artificial cerebellum than enables robotic human-like object handling

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University of Granada researchers have developed an artificial cerebellum (a biologically-inspired adaptive microcircuit) that controls a robotic arm with human-like precision. The cerebellum is the part of the human brain that controls the locomotor system and coordinates body movements.

To date, although robot designers have achieved very precise movements, such movements are performed at very high speed, require strong forces and are power consuming. This approach cannot be applied to robots that interact with humans, as a malfunction might be potentially dangerous.

To solve this challenge, University of Granada researchers have implemented a new cerebellar spiking model that adapts to corrections and stores their sensorial effects; in addition, it records motor commands to predict the action or movement to be performed by the robotic arm. This cerebellar model allows the user to articulate a state-of-the-art robotic arm with extraordinary mobility.

Automatic Learning

The developers of the new cerebellar model have obtained a robot that performs automatic learning by extracting the input layer functionalities of the brain cortex. Furthermore, they have developed two control systems that enable accurate and robust control of the robotic arm during object handling.

The synergy between the cerebellum and the automatic control system enables robot’s adaptability to changing conditions i.e. the robot can interact with humans. The biologically-inspired architectures used in this model combine the error training approach with predictive adaptive control.

The designers of this model are Silvia Tolu, Jesús Garrido and Eduardo Ros Vidal, at the University of Granada Department of Computer Architecture and Technology, and the University of Almería researcher Richard Carrillo.

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Researchers develop an artificial cerebellum than enables robotic human-like object handling

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University of Granada researchers have developed an artificial cerebellum (a biologically-inspired adaptive microcircuit) that controls a robotic arm with human-like precision. The cerebellum is the part of the human brain that controls the locomotor system and coordinates body movements.

To date, although robot designers have achieved very precise movements, such movements are performed at very high speed, require strong forces and are power consuming. This approach cannot be applied to robots that interact with humans, as a malfunction might be potentially dangerous.

To solve this challenge, University of Granada researchers have implemented a new cerebellar spiking model that adapts to corrections and stores their sensorial effects; in addition, it records motor commands to predict the action or movement to be performed by the robotic arm. This cerebellar model allows the user to articulate a state-of-the-art robotic arm with extraordinary mobility.

Automatic Learning

The developers of the new cerebellar model have obtained a robot that performs automatic learning by extracting the input layer functionalities of the brain cortex. Furthermore, they have developed two control systems that enable accurate and robust control of the robotic arm during object handling.

The synergy between the cerebellum and the automatic control system enables robot’s adaptability to changing conditions i.e. the robot can interact with humans. The biologically-inspired architectures used in this model combine the error training approach with predictive adaptive control.

The designers of this model are Silvia Tolu, Jesús Garrido and Eduardo Ros Vidal, at the University of Granada Department of Computer Architecture and Technology, and the University of Almería researcher Richard Carrillo.

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Researchers develop an artificial cerebellum than enables robotic human-like object handling

Escrito por

University of Granada researchers have developed an artificial cerebellum (a biologically-inspired adaptive microcircuit) that controls a robotic arm with human-like precision. The cerebellum is the part of the human brain that controls the locomotor system and coordinates body movements.

To date, although robot designers have achieved very precise movements, such movements are performed at very high speed, require strong forces and are power consuming. This approach cannot be applied to robots that interact with humans, as a malfunction might be potentially dangerous.

To solve this challenge, University of Granada researchers have implemented a new cerebellar spiking model that adapts to corrections and stores their sensorial effects; in addition, it records motor commands to predict the action or movement to be performed by the robotic arm. This cerebellar model allows the user to articulate a state-of-the-art robotic arm with extraordinary mobility.

Automatic Learning

The developers of the new cerebellar model have obtained a robot that performs automatic learning by extracting the input layer functionalities of the brain cortex. Furthermore, they have developed two control systems that enable accurate and robust control of the robotic arm during object handling.

The synergy between the cerebellum and the automatic control system enables robot’s adaptability to changing conditions i.e. the robot can interact with humans. The biologically-inspired architectures used in this model combine the error training approach with predictive adaptive control.

The designers of this model are Silvia Tolu, Jesús Garrido and Eduardo Ros Vidal, at the University of Granada Department of Computer Architecture and Technology, and the University of Almería researcher Richard Carrillo.

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Researchers Develop an Artificial Cerebellum that Enables Robotic Human-Like Object Handling

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University of Granada researchers have developed an artificial cerebellum (a biologically-inspired adaptive microcircuit) that controls a robotic arm with human-like precision. The cerebellum is the part of the human brain that controls the locomotor system and coordinates body movements.

To date, although robot designers have achieved very precise movements, such movements are performed at very high speed, require strong forces and are power consuming. This approach cannot be applied to robots that interact with humans, as a malfunction might be potentially dangerous.

To solve this challenge, University of Granada researchers have implemented a new cerebellar spiking model that adapts to corrections and stores their sensorial effects; in addition, it records motor commands to predict the action or movement to be performed by the robotic arm. This cerebellar model allows the user to articulate a state-of-the-art robotic arm with extraordinary mobility.

Automatic Learning

The developers of the new cerebellar model have obtained a robot that performs automatic learning by extracting the input layer functionalities of the brain cortex. Furthermore, they have developed two control systems that enable accurate and robust control of the robotic arm during object handling.

The synergy between the cerebellum and the automatic control system enables robot’s adaptability to changing conditions i.e. the robot can interact with humans. The biologically-inspired architectures used in this model combine the error training approach with predictive adaptive control.

The designers of this model are Silvia Tolu, Jesús Garrido and Eduardo Ros Vidal, at the University of Granada Department of Computer Architecture and Technology, and the University of Almería researcher Richard Carrillo.

For more information visit http://www.ugr.es/

Reference:

N. R. Luque, J. A. Garrido, R. R. Carrillo, S. Tolu, E. Ros, Adaptive Cerebellar Spiking Model embedded in the control loop: Context switching and robustness against noise, International Journal of Neural Systems 21 (5) (2011) 385-401

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Researchers Develop an Artificial Cerebellum that Enables Robotic Human-Like Object Handling

Escrito por

University of Granada researchers have developed an artificial cerebellum (a biologically-inspired adaptive microcircuit) that controls a robotic arm with human-like precision. The cerebellum is the part of the human brain that controls the locomotor system and coordinates body movements.

To date, although robot designers have achieved very precise movements, such movements are performed at very high speed, require strong forces and are power consuming. This approach cannot be applied to robots that interact with humans, as a malfunction might be potentially dangerous.

To solve this challenge, University of Granada researchers have implemented a new cerebellar spiking model that adapts to corrections and stores their sensorial effects; in addition, it records motor commands to predict the action or movement to be performed by the robotic arm. This cerebellar model allows the user to articulate a state-of-the-art robotic arm with extraordinary mobility.

Automatic Learning

The developers of the new cerebellar model have obtained a robot that performs automatic learning by extracting the input layer functionalities of the brain cortex. Furthermore, they have developed two control systems that enable accurate and robust control of the robotic arm during object handling.

The synergy between the cerebellum and the automatic control system enables robot’s adaptability to changing conditions i.e. the robot can interact with humans. The biologically-inspired architectures used in this model combine the error training approach with predictive adaptive control.

The designers of this model are Silvia Tolu, Jesús Garrido and Eduardo Ros Vidal, at the University of Granada Department of Computer Architecture and Technology, and the University of Almería researcher Richard Carrillo.

For more information visit http://www.ugr.es/

Reference:

N. R. Luque, J. A. Garrido, R. R. Carrillo, S. Tolu, E. Ros, Adaptive Cerebellar Spiking Model embedded in the control loop: Context switching and robustness against noise, International Journal of Neural Systems 21 (5) (2011) 385-401

Descargar

Researchers Develop an Artificial Cerebellum that Enables Robotic Human-Like Object Handling

Escrito por

University of Granada researchers have developed an artificial cerebellum (a biologically-inspired adaptive microcircuit) that controls a robotic arm with human-like precision. The cerebellum is the part of the human brain that controls the locomotor system and coordinates body movements.

To date, although robot designers have achieved very precise movements, such movements are performed at very high speed, require strong forces and are power consuming. This approach cannot be applied to robots that interact with humans, as a malfunction might be potentially dangerous.

To solve this challenge, University of Granada researchers have implemented a new cerebellar spiking model that adapts to corrections and stores their sensorial effects; in addition, it records motor commands to predict the action or movement to be performed by the robotic arm. This cerebellar model allows the user to articulate a state-of-the-art robotic arm with extraordinary mobility.

Automatic Learning

The developers of the new cerebellar model have obtained a robot that performs automatic learning by extracting the input layer functionalities of the brain cortex. Furthermore, they have developed two control systems that enable accurate and robust control of the robotic arm during object handling.

The synergy between the cerebellum and the automatic control system enables robot’s adaptability to changing conditions i.e. the robot can interact with humans. The biologically-inspired architectures used in this model combine the error training approach with predictive adaptive control.

The designers of this model are Silvia Tolu, Jesús Garrido and Eduardo Ros Vidal, at the University of Granada Department of Computer Architecture and Technology, and the University of Almería researcher Richard Carrillo.

For more information visit http://www.ugr.es/

Reference:

N. R. Luque, J. A. Garrido, R. R. Carrillo, S. Tolu, E. Ros, Adaptive Cerebellar Spiking Model embedded in the control loop: Context switching and robustness against noise, International Journal of Neural Systems 21 (5) (2011) 385-401

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Ibuprofen Improves Bone Repair After Surgery or a Fracture, Study Suggests

Escrito por

A study conducted at the University of Granada has demonstrated that ibuprofen ­-a non-steroidal anti-inflammatory drug (NSAID)­- has beneficial effects on bone repair after a fracture or following bone surgery.In vitro tests demonstrated that -unlike other NSAIDs- when a therapeutic dose of ibuprofen is administered, it has no negative effects on the proliferation and synthesis of obsteoblast osteocalcin, a cell which is directly involved in the formation and regeneration of bones.Osteoblast cells are bone cells that synthesize the bone matrix. Consequently, osteoblasts play a major role in bone development, growth, maintenance and repair.

Positive Results

In an article recently published in the Journal of Bone and Mineral Metabolism, the University of Granada researchers report the positive effects of ibuprofen on bone repair. The researchers are members of the research group BIO277, which studies the effects of different pharmacological and non-pharmacological therapies on obsteoblast cells.
The primary author of this article, Concepción Ruiz Rodríguez, a professor at the University of Granada Nursing Department states that «up to date, we had little information on the effects of ibuprofen on osteoblast cells.» The University of Granada study demonstrates that a therapeutic dose of ibuprofen (5-25 µm.) does not inhibit the proliferation and synthesis of osteocalcin in the MG-63 cell line. However, when higher doses are administered (>25 µm.) they may activate other cells, which might explain the expression of membrane markers and the decrease in the phagocytic capacity.

Descargar

Ibuprofen Improves Bone Repair After Surgery or a Fracture, Study Suggests

Escrito por

A study conducted at the University of Granada has demonstrated that ibuprofen ­-a non-steroidal anti-inflammatory drug (NSAID)­- has beneficial effects on bone repair after a fracture or following bone surgery.In vitro tests demonstrated that -unlike other NSAIDs- when a therapeutic dose of ibuprofen is administered, it has no negative effects on the proliferation and synthesis of obsteoblast osteocalcin, a cell which is directly involved in the formation and regeneration of bones.Osteoblast cells are bone cells that synthesize the bone matrix. Consequently, osteoblasts play a major role in bone development, growth, maintenance and repair.

Positive Results

In an article recently published in the Journal of Bone and Mineral Metabolism, the University of Granada researchers report the positive effects of ibuprofen on bone repair. The researchers are members of the research group BIO277, which studies the effects of different pharmacological and non-pharmacological therapies on obsteoblast cells.
The primary author of this article, Concepción Ruiz Rodríguez, a professor at the University of Granada Nursing Department states that «up to date, we had little information on the effects of ibuprofen on osteoblast cells.» The University of Granada study demonstrates that a therapeutic dose of ibuprofen (5-25 µm.) does not inhibit the proliferation and synthesis of osteocalcin in the MG-63 cell line. However, when higher doses are administered (>25 µm.) they may activate other cells, which might explain the expression of membrane markers and the decrease in the phagocytic capacity.

Descargar

Ibuprofen Improves Bone Repair After Surgery or a Fracture, Study Suggests

Escrito por

A study conducted at the University of Granada has demonstrated that ibuprofen ­-a non-steroidal anti-inflammatory drug (NSAID)­- has beneficial effects on bone repair after a fracture or following bone surgery.In vitro tests demonstrated that -unlike other NSAIDs- when a therapeutic dose of ibuprofen is administered, it has no negative effects on the proliferation and synthesis of obsteoblast osteocalcin, a cell which is directly involved in the formation and regeneration of bones.Osteoblast cells are bone cells that synthesize the bone matrix. Consequently, osteoblasts play a major role in bone development, growth, maintenance and repair.

Positive Results

In an article recently published in the Journal of Bone and Mineral Metabolism, the University of Granada researchers report the positive effects of ibuprofen on bone repair. The researchers are members of the research group BIO277, which studies the effects of different pharmacological and non-pharmacological therapies on obsteoblast cells.
The primary author of this article, Concepción Ruiz Rodríguez, a professor at the University of Granada Nursing Department states that «up to date, we had little information on the effects of ibuprofen on osteoblast cells.» The University of Granada study demonstrates that a therapeutic dose of ibuprofen (5-25 µm.) does not inhibit the proliferation and synthesis of osteocalcin in the MG-63 cell line. However, when higher doses are administered (>25 µm.) they may activate other cells, which might explain the expression of membrane markers and the decrease in the phagocytic capacity.

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Realizan estudio sobre las fantasías sexuales de los hombres y las mujeres

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La Universidad de Granada realizó un estudio que ha demostrado que no existen diferencias significativas entre las fantasías sexuales que experimentan habitualmente los hombres y las mujeres, ya que ambos sexos fantasean con aspectos íntimos o románticos que involucran a la pareja. Para se trabajó con una muestra de 2.250 españoles (49,6% hombres y 50,4% mujeres), con edades comprendidas entre 18 y 73 años y que habían mantenido una relación de pareja heterosexual durante, al menos, los últimos seis meses.

Los resultados obtenidos indican que casi el 100% de hombres y mujeres ha experimentado alguna fantasía sexual de modo placentero y agradable a lo largo de su vida.

Sin embargo, existen diferencias cuando se compara la frecuencia con que se tienen determinadas fantasías en ambos sexos. En concreto se pudo observar que las mujeres experimentan de modo agradable, con mayor frecuencia que los hombres, fantasías de tipo íntimo y romántico, teniendo estos pensamientos aproximadamente algunas veces al mes. Sin embargo, los hombres piensan con mayor frecuencia que ellas en actividades exploratorias, relacionadas con sexo en grupo o búsqueda de nuevas sensaciones, como «ser promiscuo», «intercambio de parejas» o «participar en una orgía». La frecuencia de estas fantasías van desde «alguna vez en la vida» a «alguna vez al año».

Los investigadores de la Universidad de Granada advierten de que tener fantasías sexuales «favorece aspectos como el deseo o la excitación sexual, por lo que es un indicador de salud sexual». En el marco de la terapia, afirman que es necesario tener en cuenta, además de la presencia o ausencia de las fantasías, la actitud que presenta el paciente hacia estas.

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Realizan estudio sobre las fantasías sexuales de los hombres y las mujeres

Escrito por

La Universidad de Granada realizó un estudio que ha demostrado que no existen diferencias significativas entre las fantasías sexuales que experimentan habitualmente los hombres y las mujeres, ya que ambos sexos fantasean con aspectos íntimos o románticos que involucran a la pareja. Para se trabajó con una muestra de 2.250 españoles (49,6% hombres y 50,4% mujeres), con edades comprendidas entre 18 y 73 años y que habían mantenido una relación de pareja heterosexual durante, al menos, los últimos seis meses.

Los resultados obtenidos indican que casi el 100% de hombres y mujeres ha experimentado alguna fantasía sexual de modo placentero y agradable a lo largo de su vida.

Sin embargo, existen diferencias cuando se compara la frecuencia con que se tienen determinadas fantasías en ambos sexos. En concreto se pudo observar que las mujeres experimentan de modo agradable, con mayor frecuencia que los hombres, fantasías de tipo íntimo y romántico, teniendo estos pensamientos aproximadamente algunas veces al mes. Sin embargo, los hombres piensan con mayor frecuencia que ellas en actividades exploratorias, relacionadas con sexo en grupo o búsqueda de nuevas sensaciones, como «ser promiscuo», «intercambio de parejas» o «participar en una orgía». La frecuencia de estas fantasías van desde «alguna vez en la vida» a «alguna vez al año».

Los investigadores de la Universidad de Granada advierten de que tener fantasías sexuales «favorece aspectos como el deseo o la excitación sexual, por lo que es un indicador de salud sexual». En el marco de la terapia, afirman que es necesario tener en cuenta, además de la presencia o ausencia de las fantasías, la actitud que presenta el paciente hacia estas.

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